干货福利:A-Level生物学霸复习笔记(二)

重庆编辑 2020-05-31 16:49

 A-Level的生物复习笔记第二弹,今天小编继续就给大家分享一下复习干活!

 Part 2 . DNA replication

■ Occurs during interphase before the cell division to ensure each daughter cell get correct amount of genetic material.

■ DNA replicates by semi-conservative replication: Each daughter DNA molecule contains one strand from parent DNA and one newly formed strand.

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■ Process:

1. The DNA double helix structure is unwound and unzipped by helicase.

2. Both separated DNA strands are used as the template strands.

3. Free nucleotides joined with templet strand and held by the hydrogen bonds between the complementary base pairs.

4. DNA polymerase catalyses the formation of the phosphodiester bonds between DNA nucleotides.

5. Due to the new DNA strands have to formed from 5’ end to 3’ end, and the DNA is antiparallel, one daughter DNA strand is formed discontinuously. The DNA segments are connected by the DNA ligase.

6. Two identical daughter DNA molecules are formed.

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